Common Publications from the Network
- Wilde AA, Escande D, Schumacher CA, Thuringer D, Mestre M, Fiolet JW. Glibenclamide inhibition of ATP-sensitive K+ channels and ischemia-induced K+ accumulation in the mammalian heart. Pflugers Arch. 1989;414 Suppl 1:S176.
- Wilde AA, Escande D, Schumacher CA, Thuringer D, Mestre M, Fiolet JW, Janse MJ. Potassium accumulation in the globally ischemic mammalian heart. A role for the ATP-sensitive potassium channel. Circ Res. 1990 Oct;67(4):835-43.
- Demolombe S, Baro I, Pereon Y, Bliek J, Mohammad-Panah R, Pollard H, Morid S, Mannens M, Wilde A, Barhanin J, Charpentier F, Escande D. A dominant negative isoform of the long QT syndrome 1 gene product. J Biol Chem. 1998 Mar 20;273(12):6837-43.
- Priori SG, Barhanin J, Hauer RN, Haverkamp W, Jongsma HJ, Kleber AG, McKenna WJ, Roden DM, Rudy Y, Schwartz K, Schwartz PJ, Towbin JA, Wilde A. Genetic and molecular basis of cardiac arrhythmias; impact on clinical management. Study group on molecular basis of arrhythmias of the working group on arrhythmias of the european society of cardiology. Eur Heart J. 1999 Feb;20(3):174-95.
- Priori SG, Barhanin J, Hauer RN, Haverkamp W, Jongsma HJ, Kleber AG, McKenna WJ, Roden DM, Rudy Y, Schwartz K, Schwartz PJ, Towbin JA, Wilde AM. Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II. Circulation. 1999 Feb 2;99(4):518-28. Part III. Circulation. 1999;99:674-681. Eur Heart Journal 1999;20:179–195
- Priori SG, Barhanin J, Hauer RN, Haverkamp W, Jongsma HJ, Kleber AG, McKenna WJ, Roden DM, Rudy Y, Schwartz K, Schwartz PJ, Towbin JA, Wilde AM. Genetic and molecular basis of cardiac arrhythmias: impact on clinical management part III. Circulation. 1999 Feb 9;99(5):674-81.
- Roden DM, Wilde AA. Drug-induced J point elevation: a marker for genetic risk of sudden death or ECG curiosity? J Cardiovasc Electrophysiol. 1999 Feb;10(2):219-23.
- Roden DM, Spooner PJ: Inherited Long QT Syndromes: A Paradigm for Understanding Arrhythmogenesis. J Cardiovasc Electrophysiol 1999;10:1664-1683
- Nattel S, Roden DM, Escande D. A spotlight on electrophysiological remodeling and the molecular biology of ion channels. Cardiovasc Res. 1999 May;42(2):267-9.
- Schott JJ, Alshinawi C, Kyndt F, Probst V, Hoorntje TM, Hulsbeek M, Wilde AA, Escande D, Mannens MM, Le Marec H. Cardiac conduction defects associate with mutations in SCN5A. Nat Genet. 1999 Sep;23(1):20-1.
- Roden DM, Spooner PM. Inherited long QT syndromes: a paradigm for understanding arrhythmogenesis. J Cardiovasc Electrophysiol. 1999 Dec;10(12):1664-83.
- Wei J, Fish FA, Myerburg RJ, Roden DM, George AL Jr. Novel KCNQ1 mutations associated with recessive and dominant congenital long QT syndromes: evidence for variable hearing phenotype associated with R518X. Hum Mutat. 2000 Apr;15(4):387-8.
- Wilde AA, Roden DM. Predicting the long-QT genotype from clinical data: from sense to science. Circulation. 2000 Dec 5;102(23):2796-8.
- Schwartz PJ, Priori SG, Spazzolini C, Moss AJ, Vincent GM, Napolitano C, Denjoy I, Guicheney P, Breithardt G, Keating MT, Towbin JA, Beggs AH, Brink P, Wilde AA, Toivonen L, Zareba W, Robinson JL, Timothy KW, Corfield V, Wattanasirichaigoon D, Corbett C, Haverkamp W, Schulze-Bahr E, Lehmann MH, Schwartz K, Coumel P, Bloise R. Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias. Circulation. 2001 Jan 2;103(1):89-95.
- Demolombe S, Franco D, de Boer P, Kuperschmidt S, Roden D, Pereon Y, Jarry A, Moorman AF, Escande D. Differential expression of KvLQT1 and its regulator IsK in mouse epithelia. Am J Physiol Cell Physiol. 2001 Feb;280(2):C359-72.
- Myerburg RJ, Spooner PM. Opportunities for sudden death prevention: directions for new clinical and basic research. Cardiovasc Res. 2001 May;50(2):177-85.
- Demolombe S, Lande G, Charpentier F, van Roon MA, van den Hoff MJ, Toumaniantz G, Baro I, Guihard G, Le Berre N, Corbier A, de Bakker J, Opthof T, Wilde A, Moorman AF, Escande D. Transgenic mice overexpressing human KvLQT1 dominant-negative isoform. Part I: Phenotypic characterisation. Cardiovasc Res. 2001 May;50(2):314-27.
- Wedekind H, Smits JP, Schulze-Bahr E, Arnold R, Veldkamp MW, Bajanowski T, Borggrefe M, Brinkmann B, Warnecke I, Funke H, Bhuiyan ZA, Wilde AA, Breithardt G, Haverkamp W. De novo mutation in the SCN5A gene associated with early onset of sudden infant death. Circulation. 2001 Sep 4;104(10):1158-64.
- Viswanathan PC, Bezzina CR, George AL Jr, Roden DM, Wilde AA, Balser JR. Gating-dependent mechanisms for flecainide action in SCN5A-linked arrhythmia syndromes. Circulation. 2001 Sep 4;104(10):1200-5.
- Wilde AA, Escande D. LQT genotype-phenotype relationships: patients and patches.Cardiovasc Res. 2001 Sep;51(4):627-9.
- Franco D, Demolombe S, Kupershmidt S, Dumaine R, Dominguez JN, Roden D, Antzelevitch C, Escande D, Moorman AF. Divergent expression of delayed rectifier K(+) channel subunits during mouse heart development. Cardiovasc Res. 2001 Oct;52(1):65-75.
- Tan HL, Kupershmidt S, Zhang R, Stepanovic S, Roden DM, Wilde AA, Anderson ME, Balser JR. A calcium sensor in the sodium channel modulates cardiac excitability. Nature. 2002 Jan 24;415(6870):442-7.
- Smits JP, Eckardt L, Probst V, Bezzina CR, Schott JJ, Remme CA, Haverkamp W, Breithardt G, Escande D, Schulze-Bahr E, LeMarec H, Wilde AA. Genotype-phenotype relationship in Brugada syndrome: electrocardiographic features differentiate SCN5A-related patients from non-SCN5A-related patients. J Am Coll Cardiol. 2002 Jul 17;40(2):350-6.
- Herfst LJ, Potet F, Bezzina CR, Groenewegen WA, Le Marec H, Hoorntje TM, Demolombe S, Baro I, Escande D, Jongsma HJ, Wilde AA, Rook MB. Na+ channel mutation leading to loss of function and non-progressive cardiac conduction defects. J Mol Cell Cardiol. 2003 May;35(5):549-57.
- Bellocq C, van Ginneken AC, Bezzina CR, Alders M, Escande D, Mannens MM, Baro I, Wilde AA. Mutation in the KCNQ1 gene leading to the short QT-interval syndrome. Circulation. 2004 May 25;109(20):2394-7.
- Kaab S, Pfeufer A, Hinterseer M, Nabauer M, Schulze-Bahr E. Related Articles, Links Long QT syndrome. Why does sex matter? Z Kardiol. 2004 Sep;93(9):641-5.
- Antzelevitch C, Brugada P, Borggrefe M, Brugada J, Brugada R, Corrado D, Gussak I, LeMarec H, Nademanee K, Perez Riera AR, Shimizu W, Schulze-Bahr E, Tan H, Wilde A. Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association. Circulation. 2005 Feb 8;111(5):659-70. Epub 2005 Jan 17. Review. Erratum in: Circulation. 2005 Jul 26;112(4):e74.
- Antzelevitch C, Brugada P, Borggrefe M, Brugada J, Brugada R, Corrado D, Gussak I, LeMarec H, Nademanee K, Perez Riera AR, Shimizu W, Schulze-Bahr E, Tan H, Wilde A. Brugada syndrome: report of the second consensus conference. Heart Rhythm. 2005 Apr;2(4):429-40. Review. Erratum in: Heart Rhythm. 2005 Aug;2(8):905.
- Kaab S, Schulze-Bahr E. Related. Susceptibility genes and modifiers for cardiac arrhythmias. Cardiovasc Res. 2005 Aug 15;67(3):397-413.
- Bezzina CR, Wilde AA, Roden DM. The molecular genetics of arrhythmias. Cardiovasc Res. 2005 Aug 15;67(3):343-6.
- Darbar D, Yang T, Churchwell K, Wilde AA, Roden DM. Unmasking of brugada syndrome by lithium. Circulation. 2005 Sep 13;112(11):1527-31.
- Verkerk AO, Wilders R, Schulze-Bahr E, Beekman L, Bhuiyan ZA, Bertrand J, Eckardt L, Lin D, Borggrefe M, Breithardt G, Mannens MM, Tan HL, Wilde AA, Bezzina CR. Role of sequence variations in the human ether-a-go-go-related gene (HERG, KCNH2) in the Brugada syndrome. Cardiovasc Res. 2005 Dec 1;68(3):441-53. Epub 2005 Jul 25.
- Smits JP, Veldkamp MW, Bezzina CR, Bhuiyan ZA, Wedekind H, Schulze-Bahr E, Wilde AA. Substitution of a conserved alanine in the domain IIIS4-S5 linker of the cardiac sodium channel causes long QT syndrome. Cardiovasc Res. 2005 Aug 15;67(3):459-66.
- Bezzina CR, Shimizu W, Yang P, Koopmann TT, Tanck MW, Miyamoto Y, Kamakura S, Roden DM, Wilde AA. Common sodium channel promoter haplotype in asian subjects underlies variability in cardiac conduction. Circulation. 2006 Jan 24;113(3):338-44.
- Kannankeril PJ, Bhuiyan ZA, Darbar D, Mannens MMAM, Wilde AAM, Roden DM: Arrhythmogenic Right Ventricular Cardiomyopathy due to a Novel Plakophilin 2 Mutation: Wide Spectrum of Disease in Mutation Carriers Within a Family. Heart Rhythm 2006;3:939-944
- Tan HL, Bardai A, Shimizu W, Moss AJ, Schulze-Bahr E, Noda T, Wilde AA. Related Articles, Links. Genotype-specific onset of arrhythmias in congenital long-QT syndrome: possible therapy implications. Circulation. 2006 Nov 14;114(20):2096-103. Epub 2006 Nov 6.
- Hofman N, Wilde AA, Kaab S, van Langen IM, Tanck MW, Mannens MM, Hinterseer M, Beckmann BM, Tan HL. Diagnostic criteria for congenital long QT syndrome in the era of molecular genetics: do we need a scoring system? Eur Heart J. 2007 Mar;28(5):575-80. Epub 2006 Nov 7
- Imboden M, Swan H, Denjoy I, Van Langen IM, Latinen-Forsblom PJ, Napolitano C, Fressart V, Breithardt G, Berthet M, Priori S, Hainque B, Wilde AA, Schulze-Bahr E, Feingold J, Guicheney P. Related Articles, Links. Female predominance and transmission distortion in the long-QT syndrome. N Engl J Med. 2006 Dec 28;355(26):2744-51.
- Mohler PJ, Le Scouarnec S, Denjoy I, Lowe JS, Guicheney P, Caron L, Driskell IM, Schott J-J, Norris K, Kim RB, Escande D, Roden DM: Defining the Cellular Phenotype of "Ankyrin-B Syndrome" Variants: Human ANK2 Variants Associated With Clinical Phenotypes Display a Spectrum of Activities in Cardiomyocytes. Circulation 2007;115:432-441
- Paul M, Gerss J, Schulze-Bahr E, Wichter T, Vahlhaus C, Wilde AA, Breithardt G, Eckardt L. Role of programmed ventricular stimulation in patients with Brugada syndrome: a meta-analysis of worldwide published data. Eur Heart J. 2007 Sep;28(17):2126-33. Epub 2007 May 5